GET OUT OF YOUR HEAD

GET
OUT OF
YOUR HEAD

SEE IF YOUR MIGRAINE MEDICATION MEETS YOUR NEEDS

PP-NNT-MYS-0371-04JUN2025

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UNDERSTANDING ACUTE AND PREVENTIVE MIGRAINE TREATMENTS

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WHAT IS MIGRAINE?

Migraine is a type of headache characterized by recurrent attacks of moderate to severe throbbing and pulsating pain on one side of the head.¹

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MIGRAINE TREATMENT INVOLVES¹
Acute treatment

Acute treatment

Acute or "abortive" medications are taken as soon as symptoms occur to relieve pain and restore function.¹

Click here to know more.

Preventive treatment

Preventive treatment

Preventive treatment is taken daily to reduce the severity of future attacks or keep them from happening.¹

Click here to know more.

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What lifestyle hacks can help with your migraine?

There are some lifestyle changes you can make to reduce or prevent migraine attacks, including:1,2

Stress Management

Stress Management
  • Exercise
  • Relaxation techniques
  • Biofeedback
    (use of electronic devices to teach you how to control certain body functions)

Migraine Triggers Log
  • This is to help you learn what you need to avoid, such as certain foods and medicines.
  • It also helps you establish consistent sleep schedules and eating regular meals.
  • Maintain adequate hydration.

Hormone Therapy

Hormone Therapy
  • It may help some women whose migraine seems to be linked to their menstrual cycle.

Manage Obesity

Manage Obesity
  • Losing weight may be helpful with migraine.
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Take charge of your migraine journey by exploring treatment options with your healthcare provider. Understanding these choices is the next key step to managing your condition.

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Acute treatment section

Can migraine episodes
be treated?

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Migraine attacks can be successfully treated with acute medications.³

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WHAT ARE THE TYPES OF ACUTE MIGRAINE MEDICATIONS?

Acute medications fall into general classes of medicines, including analgesics, ergotamines, and triptans. Some of these are available without a prescription while others need one.3

Analgesics3
  • Nonspecific pain medications.
  • May be prescribed alone or in combination with other treatments.
  • Regular or daily use of these medications can worsen your headache.
  • Examples include aspirin, naproxen sodium, ibuprofen, and acetaminophen.
Ergotamine³
  • May work on multiple migraine pathways.
  • May be given in combination with other medications.
Triptans3
  • More specific migraine treatment.
  • Patients report better outcomes when taken early in the course of the attack.
  • Example include sumatriptan.
Gepants4,5
  • They target CGRP, which is involved in migraine pain.
  • Gepants are available in oral disintegrating tablets.
  • They have relatively lower side effects compared to many other treatments.
  • Example include rimegepant.
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caution
Remember, overusing acute migraine medications can cause headache. If you find that you need more acute medication than nine days per month, then you need to talk to your doctor!³
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Preventive treatment section

Can migraine be prevented?

Migraine cannot be cured. However, preventive approaches can reduce the frequency, severity, and duration of migraine attacks. They can also help your acute treatments work more effectively.4

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WHAT ARE THE TYPES OF PREVENTIVE
MIGRAINE TREATMENTS?

There are several types of preventive migraine treatments. Some of these treatments also have other uses, like treating high blood pressure, seizures and anxiety/depression.4

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Anti-CGRP monoclonal antibodies4
  • They target Calcitonin Gene-Related Peptide (CGRP), which is involved in migraine pain.
  • They are available as injections.
  • They have relatively lower side effects compared to many other treatments.
  • Examples include erenumab and galcanezumab
Gepants4,5
  • They target CGRP, which is involved in migraine pain.
  • Gepants are available in oral disintegrating tablets.
  • They have relatively lower side effects compared to many other treatments.
  • Example include rimegepant
Nutritional supplements, vitamins and minerals4
  • The supplement group is usually well tolerated by most people.
  • The effectiveness may not match prescription treatments.
  • Examples include magnesium oxide, vitamin B2, and Feverfew
Neuromodulation devices4
  • Neuromodulation devices use electrical currents or magnets to adjust or change activity that occurs in the brain.
  • Some devices are approved for both acute and preventive treatment.
Other options4
  • Blood pressure medications called beta blockers (like atenolol), an old migraine-preventive approach.
  • Anti-seizure medications (like topiramate and sodium valproate). They are equally effective to the previous class.
  • Medications used to treat depression (like amitriptyline). Some of the medications in this class cause weight gain.
  • Neurotoxin (OnabotulinumtoxinA) can be used for the preventive treatment of chronic migraine.
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caution
Remember, it may take several months before you start noticing results. Therefore, patience and treatment compliance are important.4 Never start a medication on your own. Always discuss with your doctor the best treatment option(s) for your case.
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References:
1. Migraine(2024) Ninds.nih.gov. Available at: https://www.ninds.nih.gov/health-information/disorders/migraine (Accessed 28 August 2024) .
2. Migraine(2021) MedlinePlus.gov. Available at: https://medlineplus.gov/migraine.html (Accessed: 26 August 2024).
3. COMMONLY USED ACUTE MIGRAINE TREATMENTS (2016) Americanmigrainefoundation.org. Available at:
https://americanmigrainefoundation.org/resource-library/acute-migraine-treatments/ (Accessed 26 August 2024).
4. MigrainePrevention 101: What It Is, When To Use It and Why (2023) Americanmigrainefoundation.org. Available at:
https://americanmigrainefoundation.org/resource-library/migraine-prevention-101/ (Accessed 26 August 2024).
5. RissardoJP, Caprara ALF. Gepants for Acute and Preventive Migraine Treatment: A Narrative Review. Brain Sci. 2022;12(12):1612. Published 2022 Nov 24.

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This material is intended solely for educational purposes. It is provided for informational use only and should not be considered a substitute for professional medical advice, diagnosis or treatment. For correct diagnosis and treatment of migraine, please consult a healthcare professional.

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DOES MY MIGRAINE
MEDICATION WORK WELL?

Find out by answering
the questionnaire¹

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HOW WELL DO YOUR MIGRAINE MEDICATIONS WORK?
Are you pain-free in 2-4 hours?
Are you pain-free in 2-4 hours?
YES
NO
Are you functioning normally in 3-4 hours?
Are you functioning normally in 3-4 hours?
YES
NO
Does your headache respond to treatment consistently at least 50% of the time?
Does your headache respond to treatment consistently at least 50% of the time?
YES
NO
Are you comfortable with taking the treatment prescribed and still able to plan your day?
Are you comfortable with taking the treatment prescribed and still able to plan your day?
YES
NO
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If you answered “No” to one or more of these questions, you need to discuss your treatment with your doctor.¹

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ARE YOU LOOKING FOR RELIABLE SOURCES OF INFORMATION ABOUT YOUR MIGRAINE?

The internet is full of information that might not always be accurate or updated. To learn more about migraine and the latest updates, be sure to check reliable sources. Click below to know more.

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Scan code to learn more about Migraine.

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This material is intended solely for educational purposes. It is provided for informational use only and should not be considered a substitute for professional medical advice, diagnosis or treatment. For correct diagnosis and treatment of migraine, please consult a healthcare professional.

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References:
1. COMMONLY USED ACUTE MIGRAINE TREATMENTS (2016) Americanmigrainefoundation.org. Available at:
https://americanmigrainefoundation.org/resource-library/acute-migraine-treatments/ (Accessed 1 September 2024).
2. Migraine (2024) Ninds.nih.gov. Available at: https://www.ninds.nih.gov/health-information/disorders/migraine (Accessed 2 September 2024)
3. Migraine (2021) Americanmigrainefoundation.org. Available at: https://americanmigrainefoundation.org/resource-library/what-is-migraine/
4. American Headache Society. (2025, August 4). Migraine Quick Guides. Available at:
https://americanheadachesociety.org/resources/primary-care/migraine-quick-guides (Accessed 22 August 2025)
5. Migraine Awareness Month (no date) Ihs-headache.org. Available at: https://ihs-headache.org/en/resources/migraine-awareness-month/ (Accessed 2 September 2024)